Antiinflammatory, Anticholinesterase and Antioxidant Acitivites of Scopoletin Isolated from Canarium Sp. (Burseraceae Kunth)
نویسندگان
چکیده
منابع مشابه
Anti-Inflammatory, Anticholinesterase, and Antioxidant Potential of Scopoletin Isolated from Canarium patentinervium Miq. (Burseraceae Kunth)
Bioassay guided fractionation of an ethanol extract of leaves of Canarium patentinervium Miq. (Burseraceae Kunth.) led to the isolation of scopoletin. The structure of this coumarin was elucidated based on spectroscopic methods including nuclear magnetic resonance (NMR-1D and 2D) and mass spectrometry. Scopoletin inhibited the enzymatic activity of 5-lipoxygenase and acetyl cholinesterase with ...
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Activity-directed isolation of the ethyl acetate, methylene chloride and n-hexane fractions of Gloiopeltis furcata resulted in the isolation of 18 compounds. Their structures were elucidated as 2-(3-hydroxy-5-oxotetrahydrofuran-3-yl)acetic acid (1), glutaric acid (2), succinic acid (3), nicotinic acid (4), (E)-4-hydroxyhex-2-enoic acid (5), cholesterol (6), 7-hydroxycholesterol (7), uridine (8)...
متن کاملThe Antiacetylcholinesterase and Antileishmanial Activities of Canarium patentinervium Miq.
In continuation of our natural and medicinal research programme on tropical rainforest plants, a bioassay guided fractionation of ethanolic extract of leaves of Canarium patentinervium Miq. (Burseraceae Kunth.) led to the isolation of scopoletin (1), scoparone (2), (+)-catechin (3), vomifoliol (4), lioxin (5), and syringic acid (6). All the compounds exhibited antiacetylcholinesterase activity ...
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The barks and leaves extracts of Canarium patentinervium Miq. (Burseraceae Kunth.) were investigated for cyclooxygenase (COX) and 5-lipoxygenase (LOX) inhibition via in vitro models. The corresponding antioxidative power of the plant extract was also tested via nonenzyme and enzyme in vitro assays. The ethanolic extract of leaves inhibited the enzymatic activity of 5-LOX, COX-1, and COX-2 with ...
متن کاملIn vitro antioxidant properties of Scopoletin
Scopoletin is a coumarin and a major component of Aegle Marmelos. In the present study, we determined the antioxidant activity of Scopoletin by employing various in vitro antioxidant assay such as 1, 1-diphenyl-2-picrul-hydrazil free radical (DPPH) scavenging, Hydrogen peroxide scavenging, superoxide radical scavenging, Hydroxyl radical scavenging activity and ferrous ion chelating activity by ...
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ژورنال
عنوان ژورنال: The Open Conference Proceedings Journal
سال: 2013
ISSN: 2210-2892
DOI: 10.2174/2210289201304010052